定量生物物理研究组

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  ANDIS is an atomic angle- and distance-dependent statistical potential devoted for protein structure quality assessment. Five angles are calculated for each atom-pair with distance < dcut (dcut is adjustable from 7.0 to 15.0 angstrom) and residue separation ≥ 7 in protein structure. the observed frequencies of atom-pair distances and corresponding angles are converted to a combined statistical potential based on the inverse boltzmann law. andis naturally integrates the atomic orientation-dependent and distance-dependent interactions. we benchmarked andis with a comprehensive list of publicly available statistical potentials. andis demonstrate a significantly better ability of native recognition than the other tested potentials.  

 

  

ANDIS Resource  

  Download ANDIS standalone program: ANDIS.zip (89MB)

  Download non-redundant PDB dataset (3519 experimental structures with Identity cutoff =20%, Resolution cutoff =2.0 angstroms, R-factor cutoff =0.25): PDBdataset.zip (115MB)

  Download 175 CASP10-13 decoy sets: CASP10-13.zip (354MB)


Reference:
   

  Zhongwang Yu, Yuangen Yao, Haiyou Deng*, Ming Yi*. ANDIS: an atomic angle- and distance-dependent statistical potential for protein structure quality assessment. BMC Bioinformatics, (2019) 20:299 [PDF]  

 

 
 

   





附件【ANDIS.zip